Our unique ProMTag Proteomics platform technology allows customers to specifically capture proteins from a variety of sources, remove all non-protein contaminants, and yield either intact proteins or peptides ready for mass spectrometry and downstream proteomics analysis.
Traditional Proteomics Methods
- Precipitation or filtration based methods
-
- Potential for sample loss
- Bias for or against certain proteins
- Incompatibility with certain buffers
-
- Separate workflows for intact proteins and digested peptides
The ProMTag Proteomics Method
- Utilizes ProMTag to reversibly label and capture entire proteomes or single proteins
-
- ProMTag labels primary amines, allowing unbiased labeling of all proteins
- Proteins are released in their original, unmodified form
-
- Yields intact proteins or digested peptides
-
- Digestion completed in 1 hour with Impact Proteomics' stabilized, modified MT-Trypsin
-
- Simple workflow, no specialized equipment required
The ProMTag Proteomics Workflow
